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One evaluation [27] discovered that acute exposure to

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Significant variations were also discovered in the timeframe of the examined well being outcomes across the critiques. While some categorized health outcomes into acute and continual, relying on the time-point of the health consequence evaluation after EC exposure, others centered on the period of EC use. One evaluation [27] discovered that acute exposure to nicotine-containing EC aerosols induced greater inflammatory cell influx and launch of pro-inflammatory cytokines, while a sub-acute exposure showed impairment of inflammatory response in mice. Chronic inhalation resulted within the downregulation of innate immunity against viral pathogens. In another review [18], long-term EC aerosol exposure was reported to have led to reduced small airway operate, emphysematous lung destruction, and transient bronchoconstriction in animal models. One evaluate [18] reported impaired lung perform, measured by spirometry, in tobacco-naïve EC users compared to by no means customers.

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